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HH5561 Health Economics and Decision Modelling Assignment, UOG, UK

The assignment involves analyzing a decision model provided in Excel worksheets. Key tasks include:

Programming the Decision Model

Use the provided structure and data for a stylized testing intervention.

Performing Sensitivity Analysis

Assess how different inputs influence the model’s outcomes.

Reporting Results

Write a short report summarizing findings from the model and analysis.

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Submission Details

Report Word Limit: Up to 1,000 words, divided into:

Results (~800 words): Present base case results and sensitivity analysis.
Conclusions (~200 words): Provide decision-making insights based on the analysis.
References: Use Harvard Referencing Style consistently.

Formatting Guidelines:

Use clear headings, tables, and figures where necessary.
Ensure tables and figures contribute to the analysis and are legible.
Avoid redundant data in visual elements.

Worksheets Provided

Introduction: Overview of assessment details.
Conceptual Model: Diagram of a decision tree representing the model structure.
Data: Input parameters for the model, including clinical, cost, and outcome details.

Decision Problem

Population: Patients admitted to hospital with suspected severe infection.
Intervention: Adding a test to the clinical pathway to guide antibiotic use.
Comparator: Existing clinical practice without the test.
Outcomes: Costs, Quality Adjusted Life Years (QALYs), incremental cost-effectiveness ratio (ICER), and incremental monetary net benefit (INMB).

Model Summary

Structure: Decision tree.
Time Horizon: 12 months.
Perspective: Health care payer (Canadian dollars).
Follow-up Periods:

1 Month: Assess outcomes post-hospital stay.
12 Months: Evaluate infection resolution and symptoms.

Potential Patient States:

Alive (with/without complications).
Dead (with/without antibiotics)

Clinical Parameters

 

Parameter
Value (Mean)
Standard Error
Notes

Mortality

Baseline (current practice)
0.15
0.02
1-month follow-up

RR (Testing strategy)
0.9
0.03

Mortality after complications
0.3
0.06
12-month follow-up

Mortality (no complications)
0.05
0.01

Complications

Baseline (current practice)
0.25
0.04

RR (Testing strategy)
0.75
0.12

Antibiotic Initiation

Baseline (current practice)
0.85
0.07

RR (Testing strategy)
0.65
0.09

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Cost Parameters (CAN $)

 

Parameter
Value (Mean)
Standard Error
Notes

Testing Costs
$250.00
NA

Antibiotics
$50.00
NA

Inpatient Stay (Complications)
$17,500.00
500
At 1 month

Inpatient Stay (Patient Died)
$12,500.00
350
At 1 month

Inpatient Stay (No Complications)
$4,500.00
300
At 1 month

Outcome Parameters

 

Parameter
Value (Mean)
Standard Error
Notes

Alive at 1 Month (QALY)
0.1
NA

Alive at 12 Months (QALY)
0.75
NA

QALY Decrement for Complications
-0.05
NA

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